Old antibiotics target TB with a new trick.
| Autor: | Zullo AJ; Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA., Lee S |
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| Jazyk: | angličtina |
| Zdroj: | Cell host & microbe [Cell Host Microbe] 2012 May 17; Vol. 11 (5), pp. 419-20. |
| DOI: | 10.1016/j.chom.2012.05.002 |
| Abstrakt: | Autophagy is now recognized as a cellular defense mechanism that can restrict the growth of Mycobacterium tuberculosis (Mtb). In this issue of Cell Host & Microbe, Kim et al. (2012) demonstrate that antibiotics routinely used to treat Mtb infection elicit a host autophagy response critical for bacterial clearance. (Copyright © 2012 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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