T cell acute lymphoblastic leukaemia presenting with sudden onset right oculomotor nerve palsy with normal neuroradiography and cerebrospinal fluid studies.

Autor: Bhatt VR; Department Of Medicine, Staten Island University Hospital, Staten Island, New York, USA., Naqi M, Bartaula R, Murukutla S, Misra S, Popalzai M, Paramanathan K, Dai Q
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2012 Mar 27; Vol. 2012. Date of Electronic Publication: 2012 Mar 27.
DOI: 10.1136/bcr.01.2012.5685
Abstrakt: Leptomeningeal disease presenting with neurological dysfunction is not uncommon in leukaemia. However, it is often accompanied by abnormalities in cerebrospinal fluid (CSF) studies and/or neuroradiography. Here, the authors describe a case of a young patient presenting with sudden onset right oculomotor nerve palsy with normal neuroradiography and CSF studies, who was subsequently diagnosed to have T cell acute lymphoblastic leukaemia (T-ALL). This case highlights that neurological manifestations can be the initial presenting feature of T-ALL and can occur suddenly despite normal neuroradiography and initial CSF studies.
Databáze: MEDLINE