| Autor: |
Turnbull WB; School of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK. w.b.turnbull@leeds.ac.uk, Stalford SA |
| Jazyk: |
angličtina |
| Zdroj: |
Organic & biomolecular chemistry [Org Biomol Chem] 2012 Aug 14; Vol. 10 (30), pp. 5698-706. Date of Electronic Publication: 2012 May 10. |
| DOI: |
10.1039/c2ob25630d |
| Abstrakt: |
Ten years ago an unusual sugar was discovered in a cell wall polysaccharide of Mycobacterium tuberculosis. Structural elucidation revealed the presence of the first thiosugar in a bacterial polysaccharide. Synthetic studies have helped to define its relative and absolute configuration as α-D-methylthioxylofuranosyl. While its biosynthetic origins remain the subject of speculation, work has begun to define its possible biological roles. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
