Facile preparation of amine and amino acid adducts of [60]fullerene using chlorofullerene C60Cl6 as a precursor.

Autor: Kornev AB; IPCP RAS, Semenov Prospect 1, Chernogolovka 141432, Russia., Khakina EA, Troyanov SI, Kushch AA, Peregudov A, Vasilchenko A, Deryabin DG, Martynenko VM, Troshin PA
Jazyk: angličtina
Zdroj: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2012 Jun 04; Vol. 48 (44), pp. 5461-3. Date of Electronic Publication: 2012 Apr 26.
DOI: 10.1039/c2cc00071g
Abstrakt: We report a general synthetic approach to the preparation of highly functionalized amine and amino acid derivatives of [60]fullerene starting from readily available chlorofullerene C(60)Cl(6). The synthesized water-soluble amino acid derivative of C(60) demonstrated pronounced antiviral activity, while the cationic amine-based compound showed strong antibacterial action in vitro.
Databáze: MEDLINE