Hierarchical formation of supramolecular transient networks in water: a modular injectable delivery system.
| Autor: | Dankers PY; Institute for Complex Molecular Systems, Eindhoven University of Technology, The Netherlands., Hermans TM, Baughman TW, Kamikawa Y, Kieltyka RE, Bastings MM, Janssen HM, Sommerdijk NA, Larsen A, van Luyn MJ, Bosman AW, Popa ER, Fytas G, Meijer EW |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2012 May 22; Vol. 24 (20), pp. 2703-9. Date of Electronic Publication: 2012 Apr 23. |
| DOI: | 10.1002/adma.201104072 |
| Abstrakt: | A modular one-component supramolecular transient network in water, based on poly(ethylene glycol) and end-capped with four-fold hydrogen bonding units, is reported. Due to its nonlinear structural formation, this system allows active proteins to be added to the hydrogel during formation. Once implanted in vivo it releases the protein by erosion of both the protein and polymer via dissolution. (Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|
Plný text