[Hetero-oligoproteins containing pancreatic ribonuclease--enzyme conjugates of prolonged action].

Autor: Goriacheva LK, Medvedev ML, Samsonov GV, Ponomareva RB
Jazyk: ruština
Zdroj: Voprosy meditsinskoi khimii [Vopr Med Khim] 1990 Sep-Oct; Vol. 36 (5), pp. 4-6.
Abstrakt: Conjugates containing blood serum albumin and pancreatic ribonuclease, produced by means of polycondensation reaction, exhibited higher half-life in rabbit circulation as compared with non-modified enzyme. Presence of the protein-carrier contributed to elevation of the ribonuclease therapeutic efficiency and enabled to decrease the quantity of injections.
Databáze: MEDLINE