Autor: |
Kresch-Tronik NS; Servicio de Dermatología, Hospital General 'Dr Manuel Gea González', Tlalpan 14080, Mexico., Carrillo-Casas EM; Departamento de Biología Molecular e Histocompatibilidad, Hospital General 'Dr Manuel Gea González', Tlalpan 14080, Mexico., Arenas R; Departamento de Micología, Hospital General 'Dr Manuel Gea González', Tlalpan 14080, Mexico., Atoche C; Departamento de Micología, Centro Dermatológico 'Dr Fernando Latapí'. Mérida, Yucatán, Mexico., Ochoa-Carrera LA; Departamento de Ecología de Agentes Patógenos, Hospital General 'Dr Manuel Gea González', Tlalpan 14080, Mexico., Xicohtencatl-Cortes J; Departamento de Infectología, Hospital Infantil de México 'Federico Gómez', Mexico City, Mexico., Manjarrez-Hernández ÁH; Departamento de Salud Pública, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico., Hernández-Castro R; Departamento de Ecología de Agentes Patógenos, Hospital General 'Dr Manuel Gea González', Tlalpan 14080, Mexico. |
Abstrakt: |
Mycetoma is the most frequently diagnosed deep mycosis in Mexico and is caused, in 86% of cases, by Nocardia brasiliensis. Worldwide, Nocardia harenae has not been previously reported as a causative agent of human mycetoma. Herein we report, to our knowledge, the first two human cases of mycetoma due to N. harenae in a clinical setting. The strains were identified by phenotypic and molecular techniques. Both cases were characterized by long-lasting mycetoma that had previously been failed to be cured and had shown resistance to therapy. However, in our hospital, a multidrug therapy proved to be effective in these cases. |