Eight stereoisomers of homonojirimycin from D-mannose.
Autor: | Lenagh-Snow GM; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, OX1 3TA, UK., Jenkinson SF, Newberry SJ, Kato A, Nakagawa S, Adachi I, Wormald MR, Yoshihara A, Morimoto K, Akimitsu K, Izumori K, Fleet GW |
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Jazyk: | angličtina |
Zdroj: | Organic letters [Org Lett] 2012 Apr 20; Vol. 14 (8), pp. 2050-3. Date of Electronic Publication: 2012 Apr 03. |
DOI: | 10.1021/ol3005744 |
Abstrakt: | Although there are 32 6-azidoheptitols, there are only 16 homonojirimycin (HNJ) stereoisomers. Two epimeric azidoalditols derived from d-mannose allow the synthesis in water of eight stereoisomers of HNJ. (© 2012 American Chemical Society) |
Databáze: | MEDLINE |
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