| Autor: |
Silva-Vergara ML; Infectious and Parasitic Diseases Unit, Hospital de Clínicas, Federal University of the Triângulo Mineiro, Uberaba, Minas Gerais, Brazil. marioleon.dip@mednet.com.br, de Camargo ZP, Silva PF, Abdalla MR, Sgarbieri RN, Rodrigues AM, dos Santos KC, Barata CH, Ferreira-Paim K |
| Jazyk: |
angličtina |
| Zdroj: |
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2012 Mar; Vol. 86 (3), pp. 477-80. |
| DOI: |
10.4269/ajtmh.2012.11-0441 |
| Abstrakt: |
Disseminated sporotrichosis occurs in individuals with impaired cellular immunity, such as in cases of neoplasia, transplantation, diabetes, and especially, acquired immunodeficiency syndrome. This report presents a 32-year-old Brazilian human immunodeficiency virus (HIV)-infected patient who developed a protracted condition of disseminated sporotrichosis with endocarditis, bilateral endophthalmitis, and lymphatic involvement. He needed cardiac surgery to replace the mitral valve. Sporothrix brasiliensis isolates were recovered from cultures of subcutaneous nodules and mitral valve fragments. Species identification was based on classical and molecular methods. The patient received amphotericin B for 52 days and subsequently, oral itraconazole. He remains asymptomatic, and he is on maintenance therapy with itraconazole. Despite his positive clinical outcome, he developed bilateral blindness. To our knowledge, this case is the first report of endocarditis and endophthalmitis caused by S. brasiliensis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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