The excessive use of inhaled corticosteroids in chronic obstructive pulmonary disease.

Autor: Izquierdo Alonso JL; Servicio de Neumología, Hospital Universitario de Guadalajara, España. jlizquierdo@sescam.org, Rodríguez Glez-Moro JM
Jazyk: English; Spanish; Castilian
Zdroj: Archivos de bronconeumologia [Arch Bronconeumol] 2012 Jun; Vol. 48 (6), pp. 207-12. Date of Electronic Publication: 2012 Mar 03.
DOI: 10.1016/j.arbres.2012.01.002
Abstrakt: Despite the fact that the recommendations of the main clinical guidelines have restricted the indications for inhaled corticosteroids in chronic obstructive pulmonary disease (COPD), currently more than 80% of patients are receiving this treatment in Spain, mostly with high doses. A detailed review of the literature does not justify the use of these high doses, a position that agrees with the recommendations of the FDA. A re-evaluation of their safety, the consistency of the data on their efficacy showing similar results with moderate doses and a better patient selection require the use of this treatment in COPD patients to be reconsidered.
(Copyright © 2011 SEPAR. Published by Elsevier Espana. All rights reserved.)
Databáze: MEDLINE
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