| Autor: |
Burlakova EV, Dukhovich FS, Gorbatova EN, Gaintseva VD, Zhizhina GP, Zavarykina TM, Molochkina EM, Pal'mina NP, Smotriaeva MA, Treshchenkova IuA, Fatkullina LD, Shishkina LN, Mal'tseva EL |
| Jazyk: |
ruština |
| Zdroj: |
Radiatsionnaia biologiia, radioecologiia [Radiats Biol Radioecol] 2011 Nov-Dec; Vol. 51 (6), pp. 660-9. |
| Abstrakt: |
A new class of substances exhibiting radioprotective and radiosensitizing effects depending on the concentration of the substance has been found. The radioprotective effect is probably due to the resonant absorption of radiation energy and its transformation into low-energy forms, as well as reactions with water radiolysis products. We studied the effects of 2,5-difeniloxazole and di[2-(5-feniloxazolil)]benzene in various concentrations in conjunction with irradiation on the growth of melanoma B-16 in mice and the average time of their lives. When using individual doses of irradiation and doses of preparations, we observed an increase in the average lifetime of mice and a reduced tumor size. These data allow us to conclude about the possibility of using these substances in the radiotherapy of tumors. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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