Lung Cancer and Human Papilloma Viruses (HPVs): Examining the Molecular Evidence.

Autor: Prabhu PR; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India., Jayalekshmi D, Pillai MR
Jazyk: angličtina
Zdroj: Journal of oncology [J Oncol] 2012; Vol. 2012, pp. 750270. Date of Electronic Publication: 2012 Jan 26.
DOI: 10.1155/2012/750270
Abstrakt: Human papilloma virus (HPV), known to be an etiological agent for genital cancers, has been suggested also to be a possible contributory agent for lung cancer. Alternatively, lung cancer, formerly considered to be solely a smoker's disease, may now be more appropriately categorised into never smoker's and smoker's lung cancer. Through this paper we attempt to bring forth the current knowledge regarding mechanisms of HPV gaining access into the lung tissue, various strategies involved in HPV-associated tumorigenesis in lung tissue.
Databáze: MEDLINE