Intravenous thrombolysis is more effective in ischemic cardioembolic strokes than in non-cardioembolic?
| Autor: | Rocha S; Neurology Department, Braga Hospital, Portugal. sofiar@ufp.edu.pt, Pires A, Gomes J, Rocha J, Sousa F, Pinho J, Rodrigues M, Ferreira C, Machado A, Maré R, Fontes JR |
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| Jazyk: | angličtina |
| Zdroj: | Arquivos de neuro-psiquiatria [Arq Neuropsiquiatr] 2011 Dec; Vol. 69 (6), pp. 905-9. |
| DOI: | 10.1590/s0004-282x2011000700011 |
| Abstrakt: | Unlabelled: It was suggested that intravenous thrombolysis (IT) leads to larger extent recanalization in cardioembolic stroke. In this work we assess if this has beneficial clinical traduction. Method: We evaluated 177 patients undergoing IT, which were categorized into cardioembolic (CE) and non-cardioembolic (NCE). National Institutes of Health Stroke Scale (NIHSS) and modified Rankin scale were compared. Results: The mean age was 67.4 ± 12.01 and 53.8% were male. The mean NIHSS was: 14 (admission), 9 (24 h) and 6 (discharge), similar in subgroups. The difference between NIHSS at admission and 24 hours was 4.17 ± 4.92 (CE: 4.08 ± 4.71; NCE: 4.27 ± 5.17, p=0.900) and at admission and discharge there was an average difference of 6.74 ± 5.58 (CE: 6.97 ± 5.68; NCE: 6.49 ± 5.49, p=0.622). The mRS at discharge and 3 months was not significantly different by subtype, although individuals whose event was NCE are more independent at 3 months. Conclusion: Ours findings argue against a specific paper of IT in CE. It can result from heterogeneity of NCE group. |
| Databáze: | MEDLINE |
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