[The proliferative kinetics and acid-soluble proteins of the nuclear chromatin in tumor cells with a modified polyamine level].

Autor: Negreĭ GZ, Ianish IuV, Zavelevich MP, Shliakhovenko VA
Jazyk: ruština
Zdroj: Eksperimental'naia onkologiia [Eksp Onkol] 1990; Vol. 12 (5), pp. 65-7.
Abstrakt: The inhibition of polyamine synthesis by DFMO (2.7 x 10(-3) M) resulted in a decrease of proliferation rate of L and OH-1 cells. The patterns of acid-soluble nuclear proteins were studied by the SDS electrophoresis. The content of protein fraction with molecular weight 25 kD was shown to correlate with the rate of proliferation of cell cultures.
Databáze: MEDLINE