Nosocomial outbreak of Pantoea agglomerans bacteraemia associated with contaminated anticoagulant citrate dextrose solution: new name, old bug?

Autor: Boszczowski I; Infection Control Department, Hospital das Clínicas, University of São Paulo, Brazil. icarobski@uol.com.br, Nóbrega de Almeida Júnior J, Peixoto de Miranda EJ, Pinheiro Freire M, Guimarães T, Chaves CE, Cais DP, Strabelli TM, Risek CF, Soares RE, Rossi F, Costa SF, Levin AS
Jazyk: angličtina
Zdroj: The Journal of hospital infection [J Hosp Infect] 2012 Mar; Vol. 80 (3), pp. 255-8. Date of Electronic Publication: 2012 Jan 13.
DOI: 10.1016/j.jhin.2011.12.006
Abstrakt: We describe an outbreak investigation of Pantoea agglomerans bacteraemia associated with anticoagulant citrate-dextrose 46% (ACD) solution prepared in-house. A healthy man presented with septic shock during plasmapheresis for granulocyte donation. The solution used for priming and blood samples were sent for culture. Identification of the isolate to species level was performed by gyrB sequencing. Typing was performed by pulsed-field gel electrophoresis (PFGE). In total, eight cases were identified during a three-week period. P. agglomerans was also cultured from six ACD solution bags. Isolates from patients and ACD bags were identical by PFGE. All isolates were susceptible to ampicillin, cephazolin, gentamicin, ciprofloxacin, cefepime and imipenem.
(Copyright © 2011 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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