Effect of epithermal neutrons on viability of glioblastoma tumor cells in vitro.

Autor: Mostovich LA; Institute of Molecular Biology and Biophysics, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk, Russia. mostovichl@gmail.ru, Gubanova NV, Kutsenko OS, Aleinik VI, Kuznetsov AS, Makarov AN, Sorokin IN, Taskaev SY, Nepomnyashchikh GI, Grigor'eva EV
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2011 Jun; Vol. 151 (2), pp. 264-7.
DOI: 10.1007/s10517-011-1304-1
Abstrakt: We studied in vitro effect of epithermal neutrons in various doses on viability of glioblastoma U87 tumor cells. Increasing the dose from 1.9 to 4.1 Sv promoted cell death. Cytofluorimetric analysis revealed no activation of apoptosis in the irradiated cells, which attested to necrotic death of the tumor cells exposed to epithermal neutron radiation.
Databáze: MEDLINE