Stochastic gene expression stabilization as a new therapeutic strategy for cancer.
| Autor: | Capp JP; LISBP (UMR CNRS 5504; UMR INRA 792), INSA de Toulouse, Toulouse, France. capp@insa-toulouse.fr |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2012 Mar; Vol. 34 (3), pp. 170-3. Date of Electronic Publication: 2012 Jan 10. |
| DOI: | 10.1002/bies.201100149 |
| Abstrakt: | Current differentiation therapies for cancer may not be effective because it might not be enough to only use molecules targeting chromatin remodelers. It may also be necessary to stabilize the re-expressed genes to convert malignant cells into benign ones. (Copyright © 2012 WILEY Periodicals, Inc.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|
Plný text