Shear wave dispersion measures liver steatosis.
| Autor: | Barry CT; School of Medicine and Dentistry, University of Rochester, Rochester, NY 14627-0126, USA., Mills B, Hah Z, Mooney RA, Ryan CK, Rubens DJ, Parker KJ |
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| Jazyk: | angličtina |
| Zdroj: | Ultrasound in medicine & biology [Ultrasound Med Biol] 2012 Feb; Vol. 38 (2), pp. 175-82. Date of Electronic Publication: 2011 Dec 16. |
| DOI: | 10.1016/j.ultrasmedbio.2011.10.019 |
| Abstrakt: | Crawling waves, which are interfering shear wave patterns, can be generated in liver tissue over a range of frequencies. Some important biomechanical properties of the liver can be determined by imaging the crawling waves using Doppler techniques and analyzing the patterns. We report that the dispersion of shear wave velocity and attenuation, that is, the frequency dependence of these parameters, are strongly correlated with the degree of steatosis in a mouse liver model, ex vivo. The results demonstrate the possibility of assessing liver steatosis using noninvasive imaging methods that are compatible with color Doppler scanners and, furthermore, suggest that liver steatosis can be separated from fibrosis by assessing the dispersion or frequency dependence of shear wave propagations. (Copyright © 2012 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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