Autor: |
Chernyshova GA, Smol'iakova VI, Plotnikov MB, Ianovskaia EA, Gurto RV, Udut VV, Kuchin AV, Chukicheva IIu |
Jazyk: |
ruština |
Zdroj: |
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 2011; Vol. 74 (9), pp. 20-2. |
Abstrakt: |
The pharmacokinetics of 4-methyl-2,6-diisobornylphenol (MDIBP) in rat blood plasma has been studied after intravenous injection. The drug concentration in the plasma was determined using a reverse-phase HPLC procedure. It is shown that MDIBP rapidly penetrates into intensively perfused organs, but is slowly eliminated from the organism (MRT value amounting to 9 h). |
Databáze: |
MEDLINE |
Externí odkaz: |
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