Primary pediatric osteosarcoma of the skull.

Autor: Kirby EJ; Craniofacial Foundation of Utah, Salt Lake City, Utah 84117, USA. ekirbymd@gmail.com, Zhou HH, Morales L Jr
Jazyk: angličtina
Zdroj: The Journal of craniofacial surgery [J Craniofac Surg] 2011 Nov; Vol. 22 (6), pp. 2399-405.
DOI: 10.1097/SCS.0b013e318231fe9b
Abstrakt: A 16-year-old adolescent boy presented with osteosarcoma of the left parieto-occipital bone with no history of radiation, Paget disease, or retinoblastoma. The tumor presented as a painless lump, which he attributed to minor trauma 5 months before presentation. Biopsy of the lesion was inconclusive. Complete surgical resection was attained. Pathology revealed a diagnosis of osteosarcoma, grade 1 to 2/3. Adjuvant chemotherapy commenced after tumor resection. Primary pediatric osteosarcoma of the skull is an exceedingly rare malignancy, with only a handful of cases ever reported. Complete surgical resection with negative margins is the key to optimizing disease-free survival. Adjuvant chemotherapy is recommended for high-grade tumors and in cases of incomplete resection.
Databáze: MEDLINE