| Autor: |
Grandi S; Department of Chemistry, University of Pavia, Pavia, Italy., Cassinelli V, Bini M, Saino E, Mustarelli P, Arciola CR, Imbriani M, Visai L |
| Jazyk: |
angličtina |
| Zdroj: |
The International journal of artificial organs [Int J Artif Organs] 2011 Sep; Vol. 34 (9), pp. 920-8. |
| DOI: |
10.5301/ijao.5000059 |
| Abstrakt: |
Bioglasses are of wide interest since they spontaneously bond and integrate with living bone in the body. By varying the glass chemistry and/or by adding some dopants, it is possible to improve their clinical applications. Gold nanoparticles (Au NPs) are a well-known antibacterial agent, as well as a unique probe for sensing and imaging applications. We report on the synthesis of a 58S bioglass doped with Au NPs at two doping levels: 0.1% wt. and 1% wt. Antibacterial properties were observed on the Gram-positive Staphylococcus aureus, whereas no significant effects were found on the Gram-negative Escherichia coli. A possible mechanism of action of Au NPs towards bacteria has been described. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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