| Autor: |
Ramalli EL Jr; Surgery and Anatomy Department, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil., Braga LH, Evora PM, Albuquerque AA, Celotto AC, Mota AL, Evora PR |
| Jazyk: |
angličtina |
| Zdroj: |
Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular [Rev Bras Cir Cardiovasc] 2011 Jul-Sep; Vol. 26 (3), pp. 440-6. |
| DOI: |
10.5935/1678-9741.20110020 |
| Abstrakt: |
Several studies show that portions of intramyocardial coronary arteries are spared of arteriosclerosis, involving morphological, embryological, biochemical and pathophysiological aspects. Endothelial function is significantly affected in the segment of transition, as estimated by the vasoactive response to Ach. These findings suggest that myocardial bridge can provide protection against arteriosclerosis by counteracting the negative effects of endothelial dysfunction. The intramyocardial portion's protection phenomenon deserves further scientific research on all research fronts. Improved morphological, biomechanical and especially physiological and embryological knowledge may be the key to a future window of opportunity for chronic arterial disease therapy and prevention. In addition, this review discusses possible therapeutic approaches for symptomatic coronary ischemia caused by myocardial bridges. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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