[Pediatric hyperglycemic hyperosmolar coma diabeticum: diagnostic evaluation and therapeutic concept].
| Autor: | Wetter J; Pädiatrische Endokrinologie und Diabetologie, Universitätskinderklinik Bonn, Germany. joachim.woelfl e@ukb.uni-bonn.de, Gohlke BC, Stutte S, Woelfle JF |
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| Jazyk: | němčina |
| Zdroj: | Klinische Padiatrie [Klin Padiatr] 2012 Jan; Vol. 224 (1), pp. 26-31. Date of Electronic Publication: 2011 Nov 09. |
| DOI: | 10.1055/s-0031-1275681 |
| Abstrakt: | Hyperglycemic hyperosmolar coma diabeticum (HHS) is a rare phenomenon in pediatric patients. It causes major morbidity and significant mortality. It is characterized by the trias of hyperglycemia, hyperosmolality and absent or mild metabolic acidosis. Major complications include cerebral edema and rhabdomyolysis. Evidence based guidelines for HHS in children are lacking. Based on a literature review we discuss treatment options in pediatric HHS und suggest a therapeutic concept. Appropriate treatment consists of adequate fluid administration and a cautious lowering of the serum glucose level. Patients should be treated on an intensive care unit and monitored closely to avoid complications. Low-dose and late insulin administration seems to be favourable. (© Georg Thieme Verlag KG Stuttgart · New York.) |
| Databáze: | MEDLINE |
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