| Autor: |
Sowunmi A; Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria Institute for Medical Research Training, University of Ibadan, Ibadan, Nigeria. akinsowunmi@hotmail.com, Akinrinola IA, Gbotosho GO, Okuboyejo TM, Happi CT |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of tropical pediatrics [J Trop Pediatr] 2012 Aug; Vol. 58 (4), pp. 263-8. Date of Electronic Publication: 2011 Nov 03. |
| DOI: |
10.1093/tropej/fmr091 |
| Abstrakt: |
A dose regimen of artesunate and amodiaquine based on arm span- or age range (DRAAAS), derived from a study of 1674 children, was compared with standard dose regimen of the same drugs calculated according to body weight (SDRAA) in 68 malarious children. Children on DRAAAS received 0.8-1.0 of artesunate/kg and 0.9-1.2 times amodiaquine/kg compared with those receiving SDRAA. Parasite and fever clearance and fall in hematocrit in the first 3 days were similar; both regimens were well tolerated. DRAAAS is simple and is efficacious. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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