[Testosterone in saliva: application to the follow-up of prostate cancer].

Autor: Navarro-Moreno MA; Sección de Hormonas, Hospital de Bellvirge, Principes de España, Barcelona, España., Rivera-Coll A
Jazyk: Spanish; Castilian
Zdroj: Revista espanola de fisiologia [Rev Esp Fisiol] 1990 Mar; Vol. 46 (1), pp. 63-8.
Abstrakt: The basic aspects of steroid hormones transport, their tissular release and the interpretation of salivary testosterone values as a reflect of the free hormone in serum are reviewed in this article, as well as the salivary testosterone applications in several disorders, with a special emphasis on prostatic carcinoma. The usefulness of salivary testosterone in the short-term (n = 4) and long-term (n = 13) follow-up of patients affected by prostatic carcinoma after medical or surgical orchiectomy has also been studied. Our results show a correlation (r = 0.62) between salivary and serum concentration values, as well as a significative decrease (p less than 0.001) in both quantities after treatment. Both these findings and the advantages inherent to the sampling obtaining, lead to the conclusion that salivary testosterone is a good alternative to serum testosterone.
Databáze: MEDLINE