[Characterization of hepatitis C virus in chronic hepatitis patients: genotypes in the State of Amazonas, Brazil].
| Autor: | Araújo AR; Fundação de Medicina Tropical do Amazonas, Manaus, Brazil., Almeida CM, Fraporti L, Garcia N, Lima TA, Maia LP, Torres KL, Tarragô AM, Victória F, Victória M, Tateno A, Levi JE, Talhari S, Malheiro A |
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| Jazyk: | portugalština |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2011 Oct; Vol. 44 (5), pp. 638-40. |
| DOI: | 10.1590/s0037-86822011000500024 |
| Abstrakt: | Introduction: In the State of Amazonas, data regarding the prevalence of different genotypes of hepatitis C virus remains scarce. Methods: The genotype of 69 HCV positive patients was determined. An in-house standardized nested-PCR was used to detect HCV RNA. Genotype assignment was based on type-specific motifs on the sequenced amplicons delimited by primers HC11/HC18 from the 5' untranslated region. Results: Of the 69 patients studied, 65.2% were male and 34.8% were female. Genotype 1 showed the greatest prevalence, followed by 3 and 2. Conclusions: These data suggesting that Manaus is the point of arrival of HCV in the State of Amazonas. |
| Databáze: | MEDLINE |
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