Reference ranges for total and calculated free and bioavailable testosterone in a young healthy women population with normal menstrual cycles or using oral contraception.

Autor: Pesant MH; Department of Medicine, Division of Endocrinology, Université de Sherbrooke, 12th Avenue North, Fleurimont, Québec, Canada J1H 5N4., Desmarais G, Fink GD, Baillargeon JP
Jazyk: angličtina
Zdroj: Clinical biochemistry [Clin Biochem] 2012 Jan; Vol. 45 (1-2), pp. 148-50. Date of Electronic Publication: 2011 Oct 14.
DOI: 10.1016/j.clinbiochem.2011.10.001
Abstrakt: Objective: Determine reference values for testosterone in women.
Design and Methods: 18-40 Year-old women with regular menses or using oral contraception were assessed by questionnaire and blood sample.
Results: In 155 women, reference values were different between women with and without hyperandrogenism for total testosterone (0.48-3.42 vs. 0.54-2.72 nmol/L) and calculated free (3-65 vs. 3-39 pmol/L) and bioavailable (0.06-1.35 vs. 0.06-0.81 nmol/L) testosterone.
Conclusion: Upper reference values for testosterone in women must be established from a well-characterized population.
(Copyright © 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE