Modular synthesis of supramolecular ureidopyrimidinone-peptide conjugates using an oxime ligation strategy.
| Autor: | Kieltyka RE; Institute for Complex Molecular Systems, and Laboratory of Chemical Biology, Eindhoven University of Technology (TU/e), PO Box 513, 5600 MB, Eindhoven, The Netherlands., Bastings MM, van Almen GC, Besenius P, Kemps EW, Dankers PY |
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| Jazyk: | angličtina |
| Zdroj: | Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2012 Feb 01; Vol. 48 (10), pp. 1452-4. Date of Electronic Publication: 2011 Oct 18. |
| DOI: | 10.1039/c1cc14728e |
| Abstrakt: | A convenient method to prepare supramolecular bioconjugates in a facile and scalable manner is by a modular approach, whereby self-assembling units and peptides are coupled using oxime chemistry. We here report syntheses of bioactive ureidopyrimidinone-based peptide conjugates, and their resultant self-assembly into fibrous structures. (This journal is © The Royal Society of Chemistry 2012) |
| Databáze: | MEDLINE |
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