Ultrasensitive diagnosis for an anthrax-protective antigen based on a polyvalent directed peptide polymer coupled to zinc oxide nanorods.

Autor: Park HY; Department of Chemistry, Hanyang University, Seoul, Korea., Gedi V, Kim J, Park HC, Han SH, Yoon MY
Jazyk: angličtina
Zdroj: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2011 Dec 01; Vol. 23 (45), pp. 5425-9. Date of Electronic Publication: 2011 Oct 14.
DOI: 10.1002/adma.201103284
Abstrakt: A flexible poly-D-lysine polymer conjugated with different target-binding peptides is demonstrated with an ultralow concentration detection limit compared to those of other conventional detection systems. This polyvalent directed peptide polymer (PDPP) exhibits increased binding affinity and detects anthrax protective antigen at low levels using a well-known zinc oxide nanorod detection system.
(Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
Databáze: MEDLINE