| Autor: |
Weinreb RN; Department of Ophthalmology, University of California, San Diego, La Jolla 92093., Caldwell DR, Goode SM, Horwitz BL, Laibovitz R, Shrader CE, Stewart RH, Williams AT |
| Jazyk: |
angličtina |
| Zdroj: |
American journal of ophthalmology [Am J Ophthalmol] 1990 Aug 15; Vol. 110 (2), pp. 189-92. |
| DOI: |
10.1016/s0002-9394(14)76990-9 |
| Abstrakt: |
In 352 patients with primary open-angle glaucoma or ocular hypertension, a multicenter double-masked, parallel-group clinical study compared the effects on intraocular pressure and ocular comfort of 0.5% betaxolol ophthalmic solution, a cardioselective beta-adrenergic blocking agent, with 0.25% betaxolol suspension. With twice-daily dosages, baseline intraocular pressure was significantly reduced (P = .0005), with no significant difference between the two groups, at Week 2 and at Months 1, 2, and 3. Further, the prevalence of ocular discomfort upon topical instillation was significantly lower for 0.25% betaxolol suspension than for 0.5% betaxolol solution (P = .0005). |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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