Mediastinal endodermal sinus tumor associated with fatal hemophagocytic syndrome.

Autor: Chaudary IU; Department of Surgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia., Bojal SA, Attia A, Al-Dossary B, Al Dayel Af, Amr SS
Jazyk: angličtina
Zdroj: Hematology/oncology and stem cell therapy [Hematol Oncol Stem Cell Ther] 2011; Vol. 4 (3), pp. 138-41.
DOI: 10.5144/1658-3876.2011.138
Abstrakt: The association of endodermal sinus tumor, known also as yolk sac tumor, of the mediastinum with hemophagocytic syndrome is exceedingly rare with only a few cases on record. We report a 24-year-old male who had a large mediastinal germ cell tumor, proven to be an endodermal sinus tumor on biopsy. The patient developed pancytopenia and coagulopathy related to associated hemophagocytic syndrome, with a fatal outcome. A brief review of the relevant literature is presented as well.
Databáze: MEDLINE