Levels of tannins and flavonoids in medicinal plants: evaluating bioprospecting strategies.

Autor: Siqueira CF; Natural Products Laboratory, Pharmacy Department, Federal University of Pernambuco, 50670-901 Recife, PE, Brazil., Cabral DL, Peixoto Sobrinho TJ, de Amorim EL, de Melo JG, Araújo TA, de Albuquerque UP
Jazyk: angličtina
Zdroj: Evidence-based complementary and alternative medicine : eCAM [Evid Based Complement Alternat Med] 2012; Vol. 2012, pp. 434782. Date of Electronic Publication: 2011 Sep 29.
DOI: 10.1155/2012/434782
Abstrakt: There are several species of plants used by traditional communities in the Brazilian semiarid. An approach used in the search for natural substances that possess therapeutic value is ethnobotany or ethnopharmacology. Active substances that have phenolic groups in their structure have great pharmacological potential. To establish a quantitative relationship between the species popularly considered to be antimicrobial, antidiabetic, and antidiarrheal, the contents of tannins and flavonoids were determined. The plant selection was based on an ethnobotanical survey conducted in a community located in the municipality of Altinho, northeastern Brazil. For determination of tannin content was utilized the technique of radial diffusion, and for flavonoids, an assay based on the complexation of aluminum chloride. The group of plants with antimicrobial indications showed a higher content of tannins compared to the control groups. The results evidence suggests a possible relationship between these compounds and the observed activity.
Databáze: MEDLINE