[Association of insulin resistance to different anthropometric measures and cardiovascular risk factors in a non-diabetic population].

Autor:	Simarro Rueda M; Centro de Salud Zona 4, Albacete, España. martasimr@gmail.com, Carbayo Herencia JA, Massó Orozco J, Artigao Rodenas LM, Carrión Valero L, Divisón Garrote JA, Torres Moreno P, López Abril J, Herrero Hernández AJ, Molina Escribano F
Jazyk:	Spanish; Castilian
Zdroj:	Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion [Endocrinol Nutr] 2011 Nov; Vol. 58 (9), pp. 464-71. Date of Electronic Publication: 2011 Oct 02.
DOI:	10.1016/j.endonu.2011.06.003
Abstrakt:	Background and Objective: Insulin resistance (IR) has been directly related to obesity, particularly central obesity, and to other cardiovascular risk factors (CVRFs). Direct IR quantification is difficult in clinical practice, and indirect methods such as HOMA (homeostasis model assessment) have therefore been developed. The aim of this study was to assess the association of IR, as measured by HOMA, with different anthropometric measures and some CVRFs. Materials and Methods: A cross-sectional, observational study was carried out in a general population sample older than 18 years in the province of Albacete, Spain. Sample size was 678 subjects. Participants completed a survey and underwent physical examinations and laboratory tests. Obesity measures included body mass index, waist perimeter, and sagittal abdominal diameter. Data analysis was performed using SPSS 15.0 software. Results: Mean values of obesity measures were higher in males as compared to females and increased with age. IR prevalence was 39.8%. All assessed anthropometric measures, decreased HDL (high density lipoprotein) cholesterol and increased non-HDL cholesterol were independently associated to the risk of IR. Conclusions: A clear association exists between different anthropometrical measures and IR in the general population. There is also an association between lipid profile cahnges and the risk of experiencing IR. (Copyright © 2011 SEEN. Published by Elsevier Espana. All rights reserved.)
Databáze:	MEDLINE
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