[Effect of expression of IL-6 cytokines in renal tissue on clinical and morphological picture of diseases in patients over 60 years with IgA-nephropathies].
| Autor: | Riabova TS, Rakitianskaia IA |
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| Jazyk: | ruština |
| Zdroj: | Advances in gerontology = Uspekhi gerontologii [Adv Gerontol] 2011; Vol. 24 (2), pp. 244-8. |
| Abstrakt: | In this paper we analyzed the expression of cytokine IL-6 in biopsy tissue of the kidneys in IgA-nephropathy patients in different age groups, its relationship with clinical and morphological picture of the disease. The study showed that IL-6 affects the formation of histopathological changes in kidney tissue and does not depend on the age of the patient. Given that the duration of the disease affects the expression of IL-6 expression in glomeruli (regardless of age of the patient) the role of IL-6 in the progression of the disease is confirmed. |
| Databáze: | MEDLINE |
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