Autor: |
Porseva VV, Shilkin VV, Korzina MB, Korobkin AA, Masliukov PM |
Jazyk: |
ruština |
Zdroj: |
Morfologiia (Saint Petersburg, Russia) [Morfologiia] 2011; Vol. 139 (3), pp. 41-5. |
Abstrakt: |
Morphological features of the TRPV1-immunoreactive neurons were studied in thoracic spinal nerve sensory ganglion in 10-, 20-, 30-, 60- and 90-day-old rats under normal conditions and after chemical deafferentation caused by capsaicin (100 mg/kg) subcutaneous injection at postnatal day 2. TRPV1-immunoreactive neurons differed in their morphometric characteristics: positive neurons had very small and small sizes, negative cells had the small, medium and large sizes. Capsaicin treatment of newborn rats was shown to change age dynamics of TRPV1-positive neurons resulting in the reduction of the average cell cross-sectional area and cell numbers during the whole period of observation. |
Databáze: |
MEDLINE |
Externí odkaz: |
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