Sexual performance of old and young male rhesus macaques following treatment with GnRH.

Autor: Phoenix CH; Oregon Regional Primate Research Center, Department of Reproductive Biology and Behavior, Beaverton 97006., Chambers KC
Jazyk: angličtina
Zdroj: Physiology & behavior [Physiol Behav] 1990 Mar; Vol. 47 (3), pp. 513-7.
DOI: 10.1016/0031-9384(90)90118-n
Abstrakt: GnRH has been reported to facilitate sexual performance in a number of species. To determine whether the same was true for rhesus monkeys we measured sexual behavior and serum levels of testosterone (T) and luteinizing hormone (LH) following control tests and after treatment with two doses of GnRH. In the first experiment, old intact (N = 11) and old T-implanted, castrated (N = 4) rhesus macaques were examined. Mean intromission rate of old intact males was significantly lower following treatment with 100 micrograms of GnRH than following control injections. Other measures of sexual behavior did not differ across treatments. There were no significant treatment effects among the old castrated males. The failure to facilitate sexual performance may have been due to the age of the males and not to the species under study. Thus, in a second experiment the effects of GnRH were examined in young rhesus males. Again, there was no facilitation of sexual performance. This cannot be accounted for by a failure of GnRH to produce a physiological response. For both old and young intact males serum levels of LH and T increased significantly after treatment with both doses of GnRH. LH but not T levels increased significantly in the T-implanted males.
Databáze: MEDLINE