| Autor: |
Mizuta N; Dept. of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine., Nishiyama A, Mizuta M, Goto M, Imai A, Umeda Y, Morita M, Sakaguchi K, Konishi E, Taguchi T |
| Jazyk: |
japonština |
| Zdroj: |
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2011 Sep; Vol. 38 (9), pp. 1491-4. |
| Abstrakt: |
We experienced a case of locally advanced breast cancer achieving a significant improvement by using a combination of docetaxel(DOC), cyclophosphamide(CPA)and trastuzumab as a primary systemic therapy.The patient was a 54-year-old woman suffering from a right breast mass, who was referred to our hospital and diagnosed with HER2-positive breast cancer with subclavicular lymph nodes metastases.The combination therapy of DOC(75 mg/m / 2), CPA(600 mg/m2)and trastuzumab(loading dose 8 mg/kg, then 6 mg/kg)for 6 courses at q3 week intervals, was started as the primary systemic therapy. After 6 courses of treatment, a right modified radical mastectomy was performed.There were a little breast cancer cells in the breast, and no axillary lymph node metastases.The combination chemotherapeutic regime with DOC, CPA and trastuzumab seems to be useful for treatment of HER2-positive breast cancer. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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