| Autor: |
de-Andrés-del-Rosario A; Department of Dermatology, Universitary Hospitalary Complex Coruña, A Coruña, Spain. ana.de.andres.del.rosario@sergas.es, Verea-Hernando MM, Yebra-Pimentel MT, Rosende-Maceiras L, Piñeyro-Molina F, Capdevila EF |
| Jazyk: |
angličtina |
| Zdroj: |
The American Journal of dermatopathology [Am J Dermatopathol] 2011 Oct; Vol. 33 (7), pp. e77-80. |
| DOI: |
10.1097/DAD.0b013e318217a97d |
| Abstrakt: |
Poststeroid panniculitis is a rare disorder usually reported in children after a sudden decrease or withdrawal of corticosteroid therapy. We report a case in an adult, a finding very rarely reported in English literature. The case report is about a 34-year-old man with multiple erythematous, firm and tender subcutaneous nodules on both thighs and legs after the withdrawal of long-term doses of dexamethasone prescribed before and after surgery for a frontoinsular anaplastic oligodendroglioma. Histopathologic study revealed mainly lobular and also septal panniculitis with fat necrosis and characteristic needle-shaped clefts in radial arrangement within fat cells and multinucleated giant cells. The lesions resolved in about 5 months, after weight loss and application of topical corticosteroids for 1 month, leaving only residual hyperpigmentation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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