Self-reported adverse reactions in 4337 healthcare workers immunizations against novel H1N1 influenza.
| Autor: | Bias H; Institute of Occupational Medicine, Social Medicine and Environmental Medicine, Johann Wolfgang Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. arbsozmed@uni-frankfurt.de., Quarcoo D, Meier-Wronski C, Wicker S, Seybold J, Nienhaus A, Groneberg DA, Roux Ad |
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| Jazyk: | angličtina |
| Zdroj: | BMC research notes [BMC Res Notes] 2011 Aug 17; Vol. 4, pp. 297. Date of Electronic Publication: 2011 Aug 17. |
| DOI: | 10.1186/1756-0500-4-297 |
| Abstrakt: | Purpose: The use of the 2009 H1N1 vaccine has generated much debate concerning safety issues among the general population and physicians. It was questioned if this is a safe vaccine. Therefore, we investigated the safety of an inactivated monovalent H1N1 pandemic influenza vaccine Methods: We focused on the H1N1 pandemic influenza vaccine Pandemrix® and applied a self reporting questionnaire in a population of healthcare workers (HCWs) and medical students at a major university hospital. Results: In total, 4337 individuals were vaccinated, consisting of 3808 HCWs and 529 medical students. The vaccination rate of the employees was higher than 40%. The majority of individuals were vaccinated in November 2009. In total, 291 of the 4337 vaccinations were reported to lead to one or more adverse reactions (6.7%). Local reactions were reported in 3.8%, myalgia and arthralgia in 3.7%, fatigue in 3.7%, headache in 3.1%. Conclusions: Our data together with available data from several national and international institutions points to a safe pandemic influenza vaccine. |
| Databáze: | MEDLINE |
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