| Autor: |
Huters AD; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Quasdorf KW, Styduhar ED, Garg NK |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of the American Chemical Society [J Am Chem Soc] 2011 Oct 12; Vol. 133 (40), pp. 15797-9. Date of Electronic Publication: 2011 Aug 11. |
| DOI: |
10.1021/ja206538k |
| Abstrakt: |
We report the first total synthesis of (-)-N-methylwelwitindolinone C isothiocyanate. Our route features a number of key transformations, including an indolyne cyclization to assemble the [4.3.1]-bicyclic scaffold, as well as a late-stage intramolecular nitrene insertion to functionalize the C11 bridgehead carbon en route to the natural product. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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