| Autor: |
Randriambelomanana JA; Service de gynécologie-obstétrique, département Mère-Enfant, CHU de Toamasina, Toamasina, Madagascar. rj-anderson@doctor.com, Rakotoarisoa H, Herinirina SA, Zafindravola BA, Andrianampanalinarivo HR |
| Jazyk: |
francouzština |
| Zdroj: |
Bulletin de la Societe de pathologie exotique (1990) [Bull Soc Pathol Exot] 2011 Oct; Vol. 104 (4), pp. 243-9. Date of Electronic Publication: 2011 Aug 04. |
| DOI: |
10.1007/s13149-011-0151-7 |
| Abstrakt: |
Malaria still represents a great cause of death in sub-Saharan African areas, mainly among pregnant women. We conducted this prospective study during two years in a malaria-endemic stable region in the east of Madagascar (Toamasina) with an aim to compare the efficacy of weekly chloroquine (CQ) and the use of intermittent presumptive treatment by sulfadoxine-pyrimethamine (SP). 519 pregnant women were included in this study (CQ = 285; SP = 256). Socio-demographical characteristics of each group were identical. We found more peripheral parasitemia (CQ = 8.07% vs SP = 2.73%; P = 0.0068) and severe malaria in the CQ group (CQ = 1.75% vs SP = 0%; P = 0.0332). Anemia was more frequent in the CQ group (CQ = 4.21% vs SP = 0.35%; P = 0.0038). Placental infestation rate was also higher in the CQ group (CQ = 7.01% vs SP = 0.39%; P = 0.00001). Low birth weight and fetal death were lower in the SP group respectively [(CQ = 4.21% vs SP = 0.78%; P = 0.0121) and (CQ = 1.75%vs SP = 0%; P = 0.0332)]. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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