| Autor: |
Biannic B; Department of Chemistry, University of Florida, P.O. Box 117200, Gainesville, FL 32611, U.S.A., Ghebreghiorgis T, Aponick A |
| Jazyk: |
angličtina |
| Zdroj: |
Beilstein journal of organic chemistry [Beilstein J Org Chem] 2011; Vol. 7, pp. 802-7. Date of Electronic Publication: 2011 Jun 14. |
| DOI: |
10.3762/bjoc.7.91 |
| Abstrakt: |
The Au(I)-catalyzed cyclization of hydroxyallylic ethers to form tetrahydropyrans is reported. Employing (acetonitrile)[(o-biphenyl)di-tert-butylphosphine]gold(I) hexafluoroantimonate, the cyclization reactions were complete within minutes to hours, depending on the substrate. The reaction progress was monitored by GC, and comparisons between substrates demonstrate that reactions of allylic alcohols are faster than the corresponding ethers. Additionally, it is reported that Reaxa QuadraPure(TM) MPA is an efficient scavenging reagent that halts the reaction progress. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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