[Experimental quality assessment of APTT-control reagent kits in the study of plasma with varying Factor VIII activity].

Autor: Staritsyna NN, Shanskaia AI, Papaian LP, Ivanova RP
Jazyk: ruština
Zdroj: Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2011 May (5), pp. 31-3.
Abstrakt: An investigation into activated partial thromboplastin time (APTT) in the plasma samples with varying Factor VIII activities has determined the following parameters of the quality of APTT-control reagent kits: coefficient of variation, linearity, sensitivity, and detection. The kit is shown to meet GOST P 51352-99 requirements. The determination of the validity coefficient of approximation has proven a directly proportional functional relationship of the APTT values to the Factor VIII activity in the bilogarithmic coordinate system. The kit may be used to diagnose hemophilia A and Willebrand disease.
Databáze: MEDLINE