Silanol: a traceless directing group for Pd-catalyzed o-alkenylation of phenols.

Autor: Huang C; Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607-7061, United States., Chattopadhyay B, Gevorgyan V
Jazyk: angličtina
Zdroj: Journal of the American Chemical Society [J Am Chem Soc] 2011 Aug 17; Vol. 133 (32), pp. 12406-9. Date of Electronic Publication: 2011 Jul 21.
DOI: 10.1021/ja204924j
Abstrakt: A silanol-directed, Pd(II)-catalyzed C-H alkenylation of phenols is reported. This work features silanol, as a novel traceless directing group, and a directed o-C-H alkenylation of phenols. This new method allows for efficient synthesis of diverse alkenylated phenols, including an estrone derivative.
Databáze: MEDLINE