Rapid CE-UV binding tests of environmentally hazardous compounds with polymer-modified magnetic nanoparticles.

Autor: Iqbal Z; Ottawa-Carleton Chemistry Institute, Department of Chemistry, Carleton University, Ottawa, ON, Canada., Alsudir S, Miah M, Lai EP
Jazyk: angličtina
Zdroj: Electrophoresis [Electrophoresis] 2011 Aug; Vol. 32 (16), pp. 2181-7. Date of Electronic Publication: 2011 Jul 18.
DOI: 10.1002/elps.201100106
Abstrakt: Hazardous compounds and bacteria in water have an adverse impact on human health and environmental ecology. Polydopamine (or polypyrrole)-coated magnetic nanoparticles and polymethacrylic acid-co-ethylene glycol dimethacrylate submicron particles were investigated for their fast binding kinetics with bisphenol A, proflavine, naphthalene acetic acid, and Escherichia coli. A new method was developed for the rapid determination of % binding by sequential injection of particles first and compounds (or E. coli) next into a fused-silica capillary for overlap binding during electrophoretic migration. Only nanolitre volumes of compounds and particles were sufficient to complete a rapid binding test. After heterogeneous binding, separation of the compounds from the particles was afforded by capillary electrophoresis. % binding was influenced by applied voltage but not current flow. In-capillary coating of particles affected the % binding of compounds.
(Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
Databáze: MEDLINE
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