Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only.

Autor: Jobsen JJ; Department of Radiation Oncology, Medisch Spectrum Twente, Haaksbergerstraat 55, 7513 ER Enschede, The Netherlands., Naudin Ten Cate L, Lybeert ML, Scholten A, van der Steen-Banasik EM, van der Palen J, Stenfert Kroese MC, Slot A, Schutter EM, Siesling S
Jazyk: angličtina
Zdroj: Obstetrics and gynecology international [Obstet Gynecol Int] 2011; Vol. 2011, pp. 962518. Date of Electronic Publication: 2011 May 04.
DOI: 10.1155/2011/962518
Abstrakt: Objective. The aim of this study is to look at possible differences in outcome between serosa and adnexal involvement stage IIIA endometrial carcinoma. Methods. 67 patients with stage IIIA endometrial carcinoma were included, 46 with adnexal involvement and 21 with serosa. A central histopathological review was performed. Results. The 7-year locoregional failure rate was (LRFR) 2.2% for adnexal involvement and 16.0% for involvement of the serosa (P = .0522). The 7-year distant metastasis-free survival was 72.7% for adnexal involvement and 58.7% for serosa (P = .3994). The 7-year disease-specific survival (DSS) was 71.8% for patients with adnexal involvement and 75.4% for patients with serosa. Conclusion. Endometrial carcinoma stage IIIA with involvement of the adnexa or serosa showed to have a comparable disease-specific survival. Locoregional control was worse for serosa involvement compared to adnexa.
Databáze: MEDLINE