| Autor: |
Zaki SR; Department of Pathology, Emory University School of Medicine, Atlanta, Georgia., Austin GE, Chan WC, Conaty AL, Trusler S, Trappier S, Lindsey RB, Swan DC |
| Jazyk: |
angličtina |
| Zdroj: |
Genes, chromosomes & cancer [Genes Chromosomes Cancer] 1990 Nov; Vol. 2 (4), pp. 266-70. |
| DOI: |
10.1002/gcc.2870020403 |
| Abstrakt: |
Oligonucleotide probes have been used to map the myeloperoxidase (MPO) gene locus to chromosome bands 17q21-22. This is in agreement with results reported using conventional cDNA probes. No evidence for the existence of a second MPO gene locus was obtained. Six synthetic 72-base oligonucleotides, corresponding to different exon regions of the MPO gene, were tritium-labeled and used as in situ hybridization probes. Synthetic oligonucleotide probes offer a useful alternative to conventional DNA probes for gene mapping. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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