Devastating intracardiac and aortic thrombosis: a case report of apparent catastrophic antiphospholipid syndrome during liver transplantation.

Autor: Gologorsky E; Department of Anesthesiology, University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, FL 33136, USA. EGologorsky@med.miami.edu, Andrews DM, Gologorsky A, Sampathi V, Sundararaman L, Govindaswamy R, Raveh Y, Tzakis AG, Pretto EA Jr
Jazyk: angličtina
Zdroj: Journal of clinical anesthesia [J Clin Anesth] 2011 Aug; Vol. 23 (5), pp. 398-402. Date of Electronic Publication: 2011 Jul 08.
DOI: 10.1016/j.jclinane.2010.07.007
Abstrakt: Fewer than 80 cases of intracardiac thrombosis and intraoperative pulmonary thromboembolism during liver transplantation have been described. We present a patient who suffered an intraoperative fulminant intracardiac and aortic thrombosis and posthumously was found to have had high anticardiolipin immunoglobulin M concentration and markers of hyperfibrinolysis in preoperatively collected plasma. Hemostatic therapy in the presence of circulating antiphospholipid antibodies and the pathogenesis of a catastrophic antiphospholipid syndrome are discussed.
(Copyright © 2011 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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