| Autor: |
Laha JK; Laboratory for Drug Discovery in Neurodegeneration, Harvard NeuroDiscovery Center, Brigham & Women's Hospital and Harvard Medical School, 65 Landsdowne Street, Cambridge, Massachusetts 02139, USA., Barolo SM, Rossi RA, Cuny GD |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of organic chemistry [J Org Chem] 2011 Aug 05; Vol. 76 (15), pp. 6421-5. Date of Electronic Publication: 2011 Jul 08. |
| DOI: |
10.1021/jo200923n |
| Abstrakt: |
A general synthetic route to prepare all four carboline regioisomers by photostimulated cyclization of anilinohalopyridines is described. The methodology affords various substituted carbolines in good to excellent yields. In the case of α-carbolines, the S(RN)1 methodology complements previously reported palladium-catalyzed cyclization approaches. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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