| Autor: |
Hung SW; Department of Engineering and System Science, National Tsing Hua University, Hsinchu 300, Taiwan., Hwang JK, Tseng F, Chang JM, Chen CC, Chieng CC |
| Jazyk: |
angličtina |
| Zdroj: |
Nanotechnology [Nanotechnology] 2006 Feb 28; Vol. 17 (4), pp. S8-S13. Date of Electronic Publication: 2006 Jan 25. |
| DOI: |
10.1088/0957-4484/17/4/002 |
| Abstrakt: |
Molecular dynamics simulations are performed on n-alkinethiol self-assembled monolayers (SAMs) and their mixture on a gold surface so that the orientations of the binding of cobra cardiotoxin and E6 protein molecules can be selected using the mixing ratio of CH3-terminated SAMs with different chain lengths. The simulations suggest that a SAM surface with different mixing ratios may provide a possible platform for aligning protein molecules with a desired orientation and for enhancing the binding energy of the protein on the designed surface. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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